Question 1

Which of the following is the most crucial pathway for blood clotting?

Accepted Answer

A)   intrinsic pathway
B)   extrinsic pathway
C)   coagulation pathway
D)   fibrinogen activation pathway
E)   prothrombin activation pathwayF) D) and E)
G) A) and E)

Question 2

How does the sequential model differ from the concerted model for allosteric enzymes?

Accepted Answer

The concerted model does not allow for a...

Question 3

What is the dual action of thrombin?

Accepted Answer

Thrombin catalyzes the hydrolysis of fib...

Question 4

Aspartyl transcarbamylase catalyzes the first step in the synthesis of ______________.

Accepted Answer

The answer of Aspartyl transcarbamylase catalyzes the first step in...

Question 5

The regulatory effects of substrates on allosteric enzymes are referred to as _______________ effects.

Accepted Answer

A)   homotropic
B)   heterotropic
C)   allotropic
D)   All of the answers are correct.
E)   None of the answers is correct.F) B) and C)
G) A) and E)

Question 6

How is trypsin activity turned off?

Accepted Answer

A)   by dephosphorylation
B)   by binding an inhibitor protein
C)   by a second cleavage
D)   All of the answers are correct.
E)   by dephosphorylation and binding an inhibitor proteinF) C) and D)
G) B) and E)

Question 7

How does cigarette smoking relate to elastase function?

Accepted Answer

<img  loading="lazy" src="/assets/images/blured-textbook.svg" class="d-inline m-1" alt="blured image" width="139" height="30">1-antitrypsin is a neutrophil protein th...

Question 8

A regulatory mechanism that is NOT readily reversible is

Accepted Answer

A)   phosphorylation.
B)   allosteric control.
C)   proteolytic cleavage.
D)   All of the answers are correct.
E)   None of the answers is correct.F) A) and E)
G) A) and D)

Question 9

Blood clotting cascades are controlled mostly by

Accepted Answer

A)   zymogen activation.
B)   phosphorylation.
C)   allosteric activation.
D)   All of the answers are correct.
E)   None of the answers is correct.F) B) and D)
G) C) and D)

Question 10

Protein kinase A is activated by the binding of ________________ to specific sites on the regulatory subunit.

Accepted Answer

cAMP

Question 11

Which of the following is an example of a zymogen?

Accepted Answer

A)   pepsinogen
B)   procarboxypeptidase
C)   T-form of ACTase
D)   All of the answers are correct.
E)   pepsinogen and procarboxypeptidaseF) A) and B)
G) A) and C)

Question 12

What regulatory mechanism relies on inhibition of the first step of the pathway by the final product of the pathway?

Accepted Answer

A)   competitive inhibition
B)   uncompetitive inhibition
C)   allosteric inhibition
D)   feed-forward inhibition
E)   feedback inhibitionF) B) and C)
G) C) and D)

Question 13

Blood serum analysis of ____________________________ isozymes is used in the diagnosis of a myocardial infarction.

Accepted Answer

lactate de...

Question 14

Why might it have been surprising to find that CTP inhibits ATCase?

Accepted Answer

The substrates for ATCase are carbamoyl ...

Question 15

Which modified amino acid is found in prothrombin that allows for Ca2+ binding?

Accepted Answer

A)   acetyl lysine
B)   phosphoserine
C)    γ\gammaγ -carboxyglutamate
D)   hydroxyproline
E)   None of the answers is correct. F) A) and C)
G) C) and D) C

Question 16

p-Hydroxymercuribenzoate displaces Zn2+ from binding to crucial ______________ residues in ATCase.

Accepted Answer

Question 17

Changes in ATCase conformation were detected by crystallizing the enzyme in the presence of PALA (N-(phosphonacetyl) -L-aspartate) . What is PALA?

Accepted Answer

A)   a radioactive tag that binds to the subunits
B)   a substrate analog that resembles the transition state
C)   a fluorescent allosteric inhibitor analog
D)   All of the answers are correct.
E)   None of the answers is correct.F) A) and B)
G) B) and D)

Question 18

A ______________ is an inactive precursor of an enzyme that is activated by a proteolytic cleavage.

Accepted Answer

zymogen or...

Question 19

The relaxed form of an allosteric enzyme has _________ affinity for the substrates than the tense form.

Accepted Answer

A)   higher
B)   equal
C)   lower
D)   no
E)   None of the answers is correct.F) None of the above
G) C) and D) A

Question 20

What term describes enzymes that are activated by proteolytic cleavage?

Accepted Answer

A)   phosphatases
B)   isozymes
C)   kinases
D)   zymogens
E)   apoenzymesF) B) and D)
G) D) and E)

Exam 10: Regulatory Strategies

Which of the following is the most crucial pathway for blood clotting?

Correct AnswerverifiedShow Answer

How does the sequential model differ from the concerted model for allosteric enzymes?

Correct AnswerverifiedThe concerted model does not allow for a...View AnswerShow Answer

What is the dual action of thrombin?

Correct AnswerverifiedThrombin catalyzes the hydrolysis of fib...View AnswerShow Answer

Aspartyl transcarbamylase catalyzes the first step in the synthesis of ______________.

Correct AnswerverifiedShow Answer

The regulatory effects of substrates on allosteric enzymes are referred to as _______________ effects.

Correct AnswerverifiedShow Answer

How is trypsin activity turned off?

Correct AnswerverifiedShow Answer

How does cigarette smoking relate to elastase function?

Correct Answerverified1-antitrypsin is a neutrophil protein th...View AnswerShow Answer

A regulatory mechanism that is NOT readily reversible is

Correct AnswerverifiedShow Answer

Blood clotting cascades are controlled mostly by

Correct AnswerverifiedShow Answer

Protein kinase A is activated by the binding of ________________ to specific sites on the regulatory subunit.

Correct AnswerverifiedcAMP

Which of the following is an example of a zymogen?

Correct AnswerverifiedShow Answer

What regulatory mechanism relies on inhibition of the first step of the pathway by the final product of the pathway?

Correct AnswerverifiedShow Answer

Blood serum analysis of ____________________________ isozymes is used in the diagnosis of a myocardial infarction.

Correct Answerverifiedlactate de...View AnswerShow Answer

Why might it have been surprising to find that CTP inhibits ATCase?

Correct AnswerverifiedThe substrates for ATCase are carbamoyl ...View AnswerShow Answer

Which modified amino acid is found in prothrombin that allows for Ca2+ binding?

Correct AnswerverifiedC

p-Hydroxymercuribenzoate displaces Zn2+ from binding to crucial ______________ residues in ATCase.

Correct AnswerverifiedShow Answer

Changes in ATCase conformation were detected by crystallizing the enzyme in the presence of PALA (N-(phosphonacetyl) -L-aspartate) . What is PALA?

Correct AnswerverifiedShow Answer

A ______________ is an inactive precursor of an enzyme that is activated by a proteolytic cleavage.

Correct Answerverifiedzymogen or...View AnswerShow Answer

The relaxed form of an allosteric enzyme has _________ affinity for the substrates than the tense form.

Correct AnswerverifiedA

What term describes enzymes that are activated by proteolytic cleavage?

Correct AnswerverifiedShow Answer

Correct Answer
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The concerted model does not allow for a...
View Answer

Correct Answer
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Thrombin catalyzes the hydrolysis of fib...
View Answer

Correct Answer
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Correct Answer
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Correct Answer
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Correct Answer
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1-antitrypsin is a neutrophil protein th...
View Answer

Correct Answer
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Correct Answer
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Correct Answer
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cAMP

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lactate de...
View Answer

Correct Answer
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The substrates for ATCase are carbamoyl ...
View Answer

Which modified amino acid is found in prothrombin that allows for Ca²⁺ binding?

Correct Answer
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C

p-Hydroxymercuribenzoate displaces Zn²⁺ from binding to crucial ______________ residues in ATCase.

Correct Answer
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Correct Answer
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Correct Answer
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zymogen or...
View Answer

Correct Answer
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A

Correct Answer
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